Melasma needs special attention because of its vulnerability to hormone, stress.
[11:47 am, 12/3/2025] SoftAd Vishal: Why choose us :-
Melasma cause & pathology is still not very clear & the most treatment options available are topical Which are not able to provide complete relief in melasma & also have high chances of recurrence. That’s why we at paradise skin & hair clinic. Also prescribed detoxify medicine (blood purifying medication) for better & long lasting results.
Most cases of melasma become chronic, untreatable or worse due to over the counter use of steroid cream.
Melasma :-
Melasma is a common pigmentary disorder of skin. In which brown & blue-grey patch appear mainly on face.
Also known as ‘mask of pregnancy’
Causes :-
prolong sun exposure
Hormonal changes
Genetic predisposition
Oral contraceptive pills
Stress
Pathophysiology :-
Melasma pathophysiology is multifactorial & not yet entirely clear.
Relation with female hormonal activity seems to be present.
Clinical feature :-
Brown & blue-grey macular pigmentation with well defined margins (mainly involving forehead, cheeks, nose)
Types :-
epidermal :- has a dark brown colour, a well defined border. Response well to treatment
Dermal :- light brown to bluish colour, difficult to treat
Mixed :- has both bluish & brown patch. Difficult to treat.
Treatment :-
1) Sun-protection :- sunscreens are most important part of therapy.
Sunscreen with at least spf 30 are advised. Tinted sunscreen are more preferred choice.
2) Tyrosinase inhibitors :- hydroquinone, retinoids, kojic acid, arbutin, vitamin-c, glutathione, azelaic acid etc
Inhibitors of melanosomes transfer :- niacinamide, retinoid, soy
Increase skin turnover :- retinoid, glycolic acid, lactic acid, azelaic acid, mandelic acid etc
3) advance treatment :-
Indication :-
How does it works :-
Procedure :-
1. Very first ask patient to wash his wash
2. Then numbing cream is applied on face for 30-45 min.
3. After 30-45 min numbing cream is cleaned.
4. Then pre decided MNRF shots where give according to skin concern & skin type.
5. Then solutions like HA, viatmin C are applied according to skin concern & soothing sheet mask is applied for better recovery.
6. At last topical anti-biotic cream is applied.
Post procedure care :-
Side effects :-
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